CD-Screen HPLC Columns for Cyclodextrin Analysis

CD-Screen columns are specialized analytical HPLC columns developed for separation and characterization work involving cyclodextrins. They support method development for parent cyclodextrins, residual underivatized material, degradation-related components and statistically substituted derivatives. Their role is especially relevant when conventional columns do not provide useful retention or selectivity for a particular cyclodextrin system.

The standard CD-Screen products use a (4-nitrophenyl)urea selector on a 4-nitrophenylcarbamidesilyl silica stationary phase. CD-Screen-IEC is the dedicated option for ionic cyclodextrin derivatives, including work involving sulfobutylether-beta-cyclodextrin. Final performance depends on the complete method, instrument, sample and operating conditions.